Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ADCYAP1R1 | P41586 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | GRK6 | P43250 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.32 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399769 | 0.89 | IDO1 (0.34) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6288796 | 0.88 | IDO1 (0.33) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL6261862 | 0.82 | MEN1 (0.43) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL6261231 | 0.81 | MAPT (0.37) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6399582 | 0.80 | ADRB2 (0.39) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL6262196 | 0.76 | ADRB2 (0.40) | ADRB2ADRB1ADRB3 | |
| SCHEMBL9768254 | 0.72 | MAPT (0.39) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL5894716 | 0.70 | KMT2A (0.49) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5894260 | 0.69 | MEN1 (0.48) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11688977 | 0.68 | ADRB2 (0.41) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551792-A1 | NOVEL BETA MIMETICS WITH EXTENDED DURATION OF ACTION, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004033412-A1 | NOVEL BETA MIMETICS WITH EXTENDED DURATION OF ACTION, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-04-22 | — | — | WO | disclosed |