SCHEMBL6263797

SCHEMBL6263797

c1ccc(COCc2nc[nH]n2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.58
HRH4 Q9H3N8 1/20 0.41
HRH3 Q9Y5N1 1/20 0.41
IDO1 P14902 2/20 0.39
KDM4E B2RXH2 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CDC7 O00311 1/20 0.38
DBF4 Q9UBU7 1/20 0.38
LMNA P02545 2/20 0.38
POLB P06746 2/20 0.38
ALDH1A1 P00352 2/20 0.38
NPC1 O15118 1/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NAAA Q02083 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL835981 0.78 TAAR1 (0.47) TSHRHRH3LMNAALDH1A1CYP1A2
Hydrochloric Acid SCHEMBL9382673 0.76 TAAR1 (0.46) TSHRHRH3LMNASMN1; SMN2CYP1A2
SCHEMBL27380 0.76 TSHR (1.00) TSHRIDO1KDM4ELMNAPOLB
Benzene SCHEMBL27997624 0.76 TSHR (1.00) TSHRIDO1KDM4ELMNAPOLB
SCHEMBL5311581 0.76 TSHR (1.00) TSHRIDO1KDM4ELMNAPOLB
SCHEMBL3644558 0.74 TSHR (0.54) TSHRCYP1A2
SCHEMBL10317949 0.73 TSHR (0.94) TSHRIDO1KDM4ELMNAPOLB
Calcium SCHEMBL2864550 0.73 TSHR (0.94) TSHRIDO1KDM4ELMNAPOLB
Methane SCHEMBL11192510 0.73 TSHR (0.94) TSHRIDO1KDM4ELMNAPOLB
SCHEMBL1009266 0.73 TSHR (0.94) TSHRIDO1KDM4ELMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005077377-A1 COMPOSITIONS THAT INCLUDE A TRITERPENE AND A CARRIER REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2005-08-25 WO disclosed
WO-2004089357-A2 ANTI-FUNGAL FORMULATION OF TRITERPENE AND ESSENTIAL OIL REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2004-10-21 WO disclosed