Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4181126 | 0.88 | ALDH1A1 (0.47) | ALDH1A1HTTSMN1; SMN2RAB9AMAPT | |
| SCHEMBL30613082 | 0.79 | NPC1 (0.57) | ALDH1A1HTTSMN1; SMN2RAB9AMAPT | |
| SCHEMBL10603799 | 0.79 | NPC1 (0.57) | ALDH1A1HTTSMN1; SMN2RAB9AMAPT | |
| SCHEMBL4170841 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HTTSMN1; SMN2RAB9AMAPT | |
| SCHEMBL23973932 | 0.76 | NPC1 (0.58) | ALDH1A1HTTSMN1; SMN2RAB9AMAPT | |
| SCHEMBL1119860 | 0.76 | AAK1 (0.61) | ALDH1A1HTTSMN1; SMN2RAB9AMAPT | |
| SCHEMBL29528391 | 0.76 | ALDH1A1 (0.71) | ALDH1A1HTTSMN1; SMN2RAB9AMAPT | |
| SCHEMBL3629114 | 0.76 | ALDH1A1 (0.71) | ALDH1A1HTTSMN1; SMN2RAB9AMAPT | |
| SCHEMBL6268777 | 0.75 | SMN1; SMN2 (0.39) | ALDH1A1HTTSMN1; SMN2RAB9AMAPT | |
| SCHEMBL6267243 | 0.74 | KMT2A (0.43) | ALDH1A1HTTSMN1; SMN2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095366-A1 | 7-ARYL 1,5-DIHYDRO-4,1-BENZOXAZEPIN-2(3H)-ONE DERIVATIVES AND THEIR USE AS PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2005-10-13 | — | — | WO | disclosed |