SCHEMBL6264667

SCHEMBL6264667

CCCCCCCCCCCCCCCCCCOC(CCCCCCCCCCCCCCCCCC)C(CO)(CO)CO.CCCCCCCCCCCCCCCCCCOP(OCCCCCCCCCCCCCCCCCC)OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
DNM1 Q05193 1/20 0.35
USP2 O75604 1/20 0.33
MEN1 O00255 1/20 0.33
THRB P10828 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
TLR2 O60603 2/20 0.32
LPAR1 Q92633 6/20 0.32
LPAR3 Q9UBY5 6/20 0.32
LPAR2 Q9HBW0 3/20 0.32
LPAR6 P43657 2/20 0.32
LPAR4 Q99677 2/20 0.32
LPAR5 Q9H1C0 2/20 0.32
SPHK1 Q9NYA1 1/20 0.31
GMNN O75496 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL672815 0.92 LMNA (0.41) LMNADNM1USP2MEN1THRB
SCHEMBL4458113 0.92 LMNA (0.41) LMNADNM1USP2MEN1THRB
SCHEMBL16196213 0.92 LMNA (0.41) LMNADNM1USP2MEN1THRB
SCHEMBL347094 0.92 LMNA (0.41) LMNADNM1USP2MEN1THRB
SCHEMBL5012928 0.92 LMNA (0.41) LMNADNM1USP2MEN1THRB
SCHEMBL5014543 0.92 LMNA (0.41) LMNADNM1USP2MEN1THRB
SCHEMBL11657835 0.92 LMNA (0.41) LMNADNM1USP2MEN1THRB
SCHEMBL2237303 0.92 LMNA (0.41) LMNADNM1USP2MEN1THRB
SCHEMBL5016259 0.92 LMNA (0.41) LMNADNM1USP2MEN1THRB
SCHEMBL94155 0.92 LMNA (0.41) LMNADNM1USP2MEN1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3452547-A1 POLYAMIDE MOULDING COMPOSITION AND MOULDED ARTICLE MADE HEREFROM EMS-Patent AG (CH) 2019-03-13 EP claimed
WO-2017191269-A1 POLYAMIDE MOULDING COMPOSITION AND MOULDED ARTICLE MADE HEREFROM EMS-PATENT AG (CH) 2017-11-09 WO claimed
US-10577478-B2 Polyamide moulding composition and multi-layered structure made therefrom EMS-PATENT AG (CH) 2020-03-03 US disclosed
US-20190136053-A1 POLYAMIDE MOULDING COMPOSITION AND MOULDED ARTICLE MADE THEREFROM EMS-PATENT AG (CH) 2019-05-09 US disclosed
EP-3452547-A1 POLYAMIDE MOULDING COMPOSITION AND MOULDED ARTICLE MADE HEREFROM EMS-Patent AG (CH) 2019-03-13 EP disclosed
EP-3312224-B1 POLYAMIDE MOULDING COMPOSITION AND MULTI-LAYERED STRUCTURE MADE HEREFROM EMS PATENT AG (CH) 2018-12-26 EP disclosed
US-20180112059-A1 POLYAMIDE MOULDING COMPOSITION AND MULTI-LAYERED STRUCTURE MADE THEREFROM EMS-PATENT AG (CH) 2018-04-26 US disclosed
EP-3312224-A1 POLYAMIDE MOULDING COMPOSITION AND MULTI-LAYERED STRUCTURE MADE HEREFROM EMS-PATENT AG (CH) 2018-04-25 EP disclosed
WO-2017191269-A1 POLYAMIDE MOULDING COMPOSITION AND MOULDED ARTICLE MADE HEREFROM EMS-PATENT AG (CH) 2017-11-09 WO disclosed
US-8383244-B2 Semiaromatic molding compounds and uses thereof EMS-PATENT AG (CH) 2013-02-26 US disclosed
US-20120321829-A1 SEMIAROMATIC MOLDING COMPOUNDS AND USES THEREOF EMS-PATENT AG (CH) 2012-12-20 US disclosed
EP-1326915-B1 POLYOLEFIN ARTICLES WITH LONG-TERM ELEVATED TEMPERATURE STABILITY CLARIANT FINANCE BVI LTD (VG) 2005-11-09 EP disclosed
US-6774170-B2 HEAT STABILIZING WITH AN OXIDIZED, NON-CATIONIZED, NON-SILYLATED SULFUR BLACK PIGMENT, A HINDERED PHENOLIC ANTIOXIDANT A SULFUR-CONTAINING SECONDARY STABILIZER, AND A HINDERED AMINE CLARIANT FINANCE (BVI) LIMITED (VG) 2004-08-10 US disclosed
EP-1326915-A2 POLYOLEFIN ARTICLES WITH LONG-TERM ELEVATED TEMPERATURE STABILITY Clariant Finance (BVI) Limited (VG) 2003-07-16 EP disclosed
US-6538056-B1 Polyethylene or polypropylene compounded with sulfur black pigment; sterically hindered phenolic antioxidant and sulfur compound stabilizer; heat resistance CLARIANT INTERNATIONAL LTD. (CH) 2003-03-25 US disclosed
US-20020156165-A1 Polyolefin articles with long-term elevated temperature stability CLARIANT INTERNATIONAL LTD. 2002-10-24 US disclosed
WO-2002031043-A2 POLYOLEFIN ARTICLES WITH LONG-TERM ELEVATED TEMPERATURE STABILITY CLARIANT FINANCE (BVI) LIMITED (VG) 2002-04-18 WO disclosed
US-5244948-A Sterically hindered piperidine-triazine compound CIBA-GEIGY CORPORATION (US) 1993-09-14 US disclosed