Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 16/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265179 | 1.00 | ALOX5 (0.63) | ALOX5POLBMAPTRAB9AALDH1A1 | |
| SCHEMBL6262617 | 0.94 | ALOX5 (0.59) | ALOX5POLBMAPTRAB9A | |
| SCHEMBL6262619 | 0.94 | ALOX5 (0.59) | ALOX5POLBMAPTRAB9A | |
| SCHEMBL4354172 | 0.84 | ALOX5 (0.54) | ALOX5MAPTRAB9AALDH1A1 | |
| SCHEMBL4354174 | 0.84 | ALOX5 (0.54) | ALOX5MAPTRAB9AALDH1A1 | |
| Acetic Acid SCHEMBL4133456 | 0.81 | ALOX5 (0.53) | ALOX5MAPTRAB9AALDH1A1 | |
| Acetic Acid SCHEMBL4133460 | 0.81 | ALOX5 (0.53) | ALOX5MAPTRAB9AALDH1A1 | |
| SCHEMBL6265121 | 0.81 | MAPT (0.55) | ALOX5POLBMAPTRAB9AALDH1A1 | |
| SCHEMBL4133860 | 0.81 | DUSP22 (0.49) | ALOX5POLBRAB9AALDH1A1 | |
| SCHEMBL4133862 | 0.81 | DUSP22 (0.49) | ALOX5POLBRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082363-A1 | THIAZOLONE COMPOUNDS FOR TREATMENT OF CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2005-09-09 | — | — | WO | claimed |
| WO-2005082363-A1 | THIAZOLONE COMPOUNDS FOR TREATMENT OF CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2005-09-09 | — | — | WO | disclosed |