SCHEMBL6265502

SCHEMBL6265502

Nc1c(I)c(NC(=O)C(O)C(O)CO)c(I)c(C(O)C(=O)NC(=O)C(O)C(O)CO)c1I

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6252055 0.91
SCHEMBL6224131 0.91
SCHEMBL7551394 0.89
SCHEMBL6264023 0.84 LMNA (0.34) LMNA
SCHEMBL6265722 0.84 LMNA (0.34) LMNA
SCHEMBL6262784 0.80 LMNA (0.30) LMNA
SCHEMBL6251970 0.79
SCHEMBL7580932 0.75
SCHEMBL7549371 0.72
SCHEMBL6253824 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1175392-B1 CONTRAST MEDIA AMERSHAM HEALTH AS (NO) 2005-06-22 EP disclosed
US-6448442-B1 X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS AMERSHAM HEALTH AS (NO) 2002-09-10 US disclosed