Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA7 | P43166 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | MB | P02144 | 1/20 | 0.57 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | RARG | P13631 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3307191 | 0.83 | NPC1 (0.60) | MAPTALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL6395775 | 0.82 | GAA (0.78) | MAPTALDH1A1CA12CA1CA2 | |
| SCHEMBL18415556 | 0.82 | RAB9A (0.68) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL208824 | 0.82 | NPC1 (0.58) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL11057395 | 0.82 | MAPT (0.46) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL5548239 | 0.82 | RAB9A (0.56) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL209203 | 0.82 | MAPT (0.69) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL11449829 | 0.81 | MAPT (0.42) | MAPTALDH1A1CA12CA1CA2 | |
| SCHEMBL626949 | 0.81 | MAPT (0.73) | MAPTALDH1A1CA12CA1CA2 | |
| SCHEMBL3955865 | 0.81 | NAPRT (0.56) | MAPTALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021800-A2 | CASPASE INHIBITORS AS THERAPEUTICS FOR NEURAL AND ORGAN INJURY AND IMAGING | BANYAN BIOMARKERS (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012021800-A2 | CASPASE INHIBITORS AS THERAPEUTICS FOR NEURAL AND ORGAN INJURY AND IMAGING | BANYAN BIOMARKERS (US) | 2012-02-16 | — | — | WO | disclosed |