Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 8/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15195848 | 0.75 | CA1 (0.41) | MEN1KMT2A | |
| SCHEMBL2314693 | 0.72 | CA1 (0.39) | MEN1KMT2A | |
| SCHEMBL3167489 | 0.72 | CA1 (0.39) | MEN1KMT2A | |
| SCHEMBL1425228 | 0.71 | LMNA (0.43) | LMNATSHRNFKB1PMP22TDP1 | |
| SCHEMBL14332242 | 0.70 | CA1 (0.38) | MEN1KMT2A | |
| Methane SCHEMBL2803151 | 0.70 | CA1 (0.38) | MEN1KMT2A | |
| Adipic Acid SCHEMBL10388302 | 0.69 | LMNA (0.85) | LMNATSHRNFKB1PMP22TDP1 | |
| Adipic Acid SCHEMBL11767551 | 0.69 | LMNA (0.85) | LMNATSHRNFKB1PMP22TDP1 | |
| Adipic Acid SCHEMBL4930 | 0.69 | LMNA (1.00) | LMNATSHRNFKB1PMP22TDP1 | |
| Adipic Acid SCHEMBL2244299 | 0.69 | LMNA (1.00) | LMNATSHRNFKB1PMP22TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252378-B1 | HYDROPHILIC BINDER FIBERS | KIMBERLY CLARK CO (US) | 2005-08-31 | — | — | EP | disclosed |
| CN-1415028-A | Biodegradable nonwoven material having fluid management properties and disposable article containing said nonwoven material | KIMBERLY CLARK CO (US) | 2003-04-30 | — | — | CN | disclosed |
| EP-1252377-A2 | BIODEGRADABLE NONWOVENS WITH FLUID MANAGEMENT PROPERTIES AND DISPOSABLE ARTICLES CONTAINING THE SAME | KIMBERLY-CLARK CORPORATION (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-1252378-A2 | HYDROPHILIC BINDER FIBERS | Kimberly-Clark Worldwide, Inc. (US) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001047368-A1 | DEGRADABLE COPOLYMERS FOR CHEWING GUM BASE | UNION CARBIDE CHEMICALS & PLASTICS (US) | 2001-07-05 | — | — | WO | disclosed |
| EP-1107999-A2 | BIODEGRADABLE THERMOPLASTIC POLYESTER COMPOSITION WITH IMPROVED WETTABILITY | Kimberly-Clark Worldwide, Inc. (US) | 2001-06-20 | — | — | EP | disclosed |
| US-6245831-B1 | THERMOPLASTIC BLEND | KIMBERLY-CLARK WORLDWIDE, INC. | 2001-06-12 | — | — | US | disclosed |
| WO-2001040555-A2 | HYDROPHILIC BINDER FIBERS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2001-06-07 | — | — | WO | disclosed |
| WO-2001040553-A2 | BIODEGRADABLE HYDROPHILIC BINDER FIBERS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2001-06-07 | — | — | WO | disclosed |
| WO-2001034215-A2 | BIODEGRADABLE NONWOVENS WITH FLUID MANAGEMENT PROPERTIES AND DISPOSABLE ARTICLES CONTAINING THE SAME | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2001-05-17 | — | — | WO | disclosed |
| US-6225388-B1 | AN ALIPHATIC POLYESTER, A MULTICARBOXYLIC ACID, AND A WETTING AGENT; BIODEGRADEABLE, EASILY PREPARED AND READILY PROCESSABLE INTO FIBERS USED FOR DISPOSAL PRODUCTS SUCH AS DIAPERS | KIMBERLY-CLARK WORLDWIDE, INC. | 2001-05-01 | — | — | US | disclosed |
| US-6218009-B1 | A BICOMPONENT BINDER FIBER COMPRISING A POLYOLEFIN CORE AND AN ALIPHATIC POLYESTER BLEND SHEATH, WHEREIN THE ALIPHATIC POLYESTER BLEND SELECTED FROM POLYBUTYLENE SUCCINATE OR COPOLYMER WITH ADIPATE OR POLYCARPROLACTONE OR MIXTURE | KIMBERLY-CLARK WORLDWIDE, INC. | 2001-04-17 | — | — | US | disclosed |
| US-6197860-B1 | DISPOSABLE ABSORBERS | KIMBERLY-CLARK WORLDWIDE, INC. | 2001-03-06 | — | — | US | disclosed |
| US-6194483-B1 | DISPOSABLE ABSORBANT MULTILAYER PADS WITH TOPSHEETS OF POLYMERS WITH MULTICOMPONENT FIBERS | KIMBERLY-CLARK WORLDWIDE, INC. | 2001-02-27 | — | — | US | disclosed |
| US-6177193-B1 | USED IN A DISPOSABLE ABSORBENT PRODUCT INTENDED FOR THE ABSORPTION OF FLUIDS SUCH AS BODY FLUIDS; COMPRISING AN ALIPHATIC POLYESTER CORE AND AN ALIPHATIC POLYESTER BLEND SHEATH | KIMBERLY-CLARK WORLDWIDE, INC. | 2001-01-23 | — | — | US | disclosed |
| WO-2000012606-A9 | BIODEGRADABLE THERMOPLASTIC POLYESTER COMPOSITION WITH IMPROVED WETTABILITY | KIMBERLY CLARK CO (US) | 2000-08-03 | — | — | WO | disclosed |
| WO-2000012606-A2 | BIODEGRADABLE THERMOPLASTIC POLYESTER COMPOSITION WITH IMPROVED WETTABILITY | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2000-03-09 | — | — | WO | disclosed |