Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.53 |
| ▸ | DRD2 | P14416 | 7/20 | 0.53 |
| ▸ | NAMPT | P43490 | 7/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266561 | 1.00 | DRD3 (0.53) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL88007 | 0.87 | DRD2 (0.56) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL88008 | 0.87 | DRD2 (0.56) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL6268361 | 0.87 | DRD3 (0.56) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL6268359 | 0.87 | DRD3 (0.56) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL6264234 | 0.85 | DRD3 (0.55) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL6264238 | 0.85 | DRD3 (0.55) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL3458107 | 0.83 | NAMPT (0.64) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL3458104 | 0.83 | NAMPT (0.64) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL81739 | 0.81 | NAMPT (0.71) | DRD3DRD2NAMPTCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1079832-B1 | USE OF VITAMIN PP COMPOUNDS | KLINGE CO CHEM PHARM FAB (DE) | 2005-11-30 | — | — | EP | claimed |