Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | MAPT | P10636 | 8/20 | 0.70 |
| ▸ | LMNA | P02545 | 6/20 | 0.70 |
| ▸ | PIP4K2A | P48426 | 4/20 | 0.70 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6269724 | 0.87 | KDM4E (1.00) | KDM4EMAPTLMNAPIP4K2ATP53 | |
| SCHEMBL6265036 | 0.87 | KDM4E (0.72) | KDM4EMAPTLMNAPIP4K2ATP53 | |
| SCHEMBL6267014 | 0.84 | KDM4E (0.71) | KDM4EMAPTLMNAPIP4K2ATP53 | |
| SCHEMBL6268886 | 0.82 | LMNA (0.73) | KDM4EMAPTLMNAPIP4K2ATP53 | |
| SCHEMBL6266583 | 0.82 | LMNA (0.73) | KDM4EMAPTLMNAPIP4K2ATP53 | |
| SCHEMBL6267297 | 0.81 | MAPT (0.81) | KDM4EMAPTLMNAPIP4K2ATP53 | |
| SCHEMBL6269716 | 0.81 | KDM4E (0.74) | KDM4EMAPTLMNAPIP4K2ATP53 | |
| SCHEMBL6271125 | 0.80 | MAPT (0.82) | KDM4EMAPTLMNAPIP4K2ATP53 | |
| SCHEMBL6267543 | 0.80 | LMNA (0.70) | KDM4EMAPTLMNAPIP4K2ATP53 | |
| SCHEMBL6264110 | 0.79 | MAPT (0.78) | KDM4EMAPTLMNAPIP4K2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047288-A1 | PYRAZOLOPYRIMIDINES AS ANTI - HEPATITS C AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2005-05-26 | — | — | WO | disclosed |