SCHEMBL6266803

SCHEMBL6266803

Brc1cccc(Oc2nc(Oc3cccc(Br)c3Br)nc(Oc3cccc(Br)c3Br)n2)c1Br

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
LMNA P02545 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
KDM4E B2RXH2 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP2C19 P33261 1/20 0.33
BACE1 P56817 2/20 0.31
NOS1 P29475 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LCK P06239 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5424007 0.92 POLB (0.33) KMT2APOLBGAALMNASMN1; SMN2
SCHEMBL5428096 0.92 POLB (0.33) KMT2APOLBGAALMNASMN1; SMN2
SCHEMBL6264228 0.88 POLB (0.40) KMT2APOLBGAALMNASMN1; SMN2
SCHEMBL29600725 0.84 TDP1 (0.40) KMT2AGAALMNASMN1; SMN2NPC1
SCHEMBL1417897 0.84 TDP1 (0.40) KMT2AGAALMNASMN1; SMN2NPC1
SCHEMBL5968103 0.82 LMNA (0.44) KMT2APOLBGAALMNASMN1; SMN2
SCHEMBL6265825 0.80 POLB (0.33) KMT2APOLBGAALMNASMN1; SMN2
SCHEMBL29354153 0.80 TDP1 (0.39) KMT2APOLBGAAMAPK1MEN1
SCHEMBL232095 0.80 TDP1 (0.39) KMT2APOLBGAAMAPK1MEN1
SCHEMBL30274289 0.77 MAPK1 (0.39) KMT2ALMNASMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230099634-A1 STYRENE-BASED RESIN COMPOSITION, FLAME RETARDANT STYRENE-BASED RESIN COMPOSITION, MOLDED BODY, AND PATCH ANTENNA PS JAPAN CORPORATION (JP) 2023-03-30 US disclosed
EP-1127917-B1 Flame-retardant thermoplastic resin composition AJINOMOTO KK (JP) 2005-11-30 EP disclosed
US-6500889-B2 BROMINATED FLAME RETARDANT, DOLOMITE AND ONE OF: HYDROTALCITE, ZINC-SUBSTITUTED HYDROTALCITE, OR ZEOLITE; HEAT STABILIZING AJINOMOTO CO., INC. (JP) 2002-12-31 US disclosed
US-20010044488-A1 Flame-retarded thermoplastic resin composition AJINOMOTO CO. INC. (JP) 2001-11-22 US disclosed
EP-1127917-A1 Flame-retardant thermoplastic resin composition Ajinomoto Co., Inc. (JP) 2001-08-29 EP disclosed