Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | NPY4R | P50391 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | CPA2 | P48052 | 1/20 | 0.45 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272641 | 1.00 | ERAP2 (0.51) | ERAP2ERAP1LNPEPPTPN1PTPN2 | |
| SCHEMBL6269554 | 0.86 | REN (0.56) | ERAP2ERAP1LNPEPRENACE2 | |
| SCHEMBL9854712 | 0.80 | REN (0.52) | PTPN1RENCCR1MMP1KISS1R | |
| SCHEMBL6270159 | 0.79 | REN (0.49) | ERAP2ERAP1LNPEPRENACE2 | |
| SCHEMBL6270870 | 0.78 | ERAP2 (0.49) | ERAP2ERAP1LNPEPPTPN1PTPN2 | |
| SCHEMBL6271560 | 0.78 | CPA1 (0.50) | ERAP2ERAP1LNPEPRENCPA1 | |
| SCHEMBL6275432 | 0.78 | ERAP2 (0.49) | ERAP2ERAP1LNPEPPTPN1PTPN2 | |
| SCHEMBL6273199 | 0.77 | CPA1 (0.47) | ERAP2ERAP1LNPEPCPA1CPB1 | |
| SCHEMBL6273945 | 0.76 | F2 (0.58) | ERAP2ERAP1LNPEPPTPN1PTPN2 | |
| SCHEMBL18064454 | 0.76 | CCR1 (0.58) | RENCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105843-A2 | HIV PROTEASE INHIBITORS | ARPIDA A/S (DK) | 2005-11-10 | — | — | WO | claimed |
| WO-2005105843-A2 | HIV PROTEASE INHIBITORS | ARPIDA A/S (DK) | 2005-11-10 | — | — | WO | disclosed |