Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 4/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.57 |
| ▸ | NAMPT | P43490 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 8/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267972 | 1.00 | DRD3 (0.57) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL6264255 | 0.91 | DRD3 (0.55) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL6264257 | 0.91 | DRD3 (0.55) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL6268378 | 0.91 | DRD3 (0.55) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL6269010 | 0.91 | DRD3 (0.55) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL6268380 | 0.91 | DRD3 (0.55) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL6269008 | 0.91 | DRD3 (0.55) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL88031 | 0.86 | DRD2 (0.60) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL88032 | 0.86 | DRD2 (0.60) | DRD3DRD2NAMPTCYP3A4CYP2C9 | |
| SCHEMBL3088770 | 0.86 | DRD3 (0.59) | DRD3DRD2NAMPTCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1079832-B1 | USE OF VITAMIN PP COMPOUNDS | KLINGE CO CHEM PHARM FAB (DE) | 2005-11-30 | — | — | EP | claimed |