Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.40 |
| ▸ | PTPRF | P10586 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.37 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.37 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267975 | 1.00 | PTPN2 (0.40) | PTPN2PTPN1PTPN6PTPRFPTPN11 | |
| SCHEMBL6267511 | 0.92 | FOLH1 (0.39) | KCNH2ADRB3ADRB1ACP1PTPN12 | |
| SCHEMBL6267508 | 0.92 | FOLH1 (0.39) | KCNH2ADRB3ADRB1ACP1PTPN12 | |
| SCHEMBL6273590 | 0.91 | MEN1 (0.37) | KCNH2L3MBTL1ADRB3ADRB1ALDH1A1 | |
| SCHEMBL6273586 | 0.91 | MEN1 (0.37) | KCNH2L3MBTL1ADRB3ADRB1ALDH1A1 | |
| SCHEMBL6272922 | 0.91 | KMT2A (0.39) | KCNH2L3MBTL1ALDH1A1ACP1PTPN12 | |
| SCHEMBL6272918 | 0.91 | KMT2A (0.39) | KCNH2L3MBTL1ALDH1A1ACP1PTPN12 | |
| SCHEMBL6273369 | 0.91 | LRRK2 (0.39) | KCNH2ADRB3ADRB1KMT2A | |
| SCHEMBL6272451 | 0.91 | KCNH2 (0.40) | KCNH2ADRB3ADRB1 | |
| SCHEMBL6273370 | 0.91 | LRRK2 (0.39) | KCNH2ADRB3ADRB1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |