Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.35 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.35 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.35 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273590 | 1.00 | MEN1 (0.37) | MEN1KMT2AKCNH2L3MBTL1ALDH1A1 | |
| SCHEMBL6267508 | 0.92 | FOLH1 (0.39) | MEN1KMT2AKCNH2ADRB1ACP1 | |
| SCHEMBL6267511 | 0.92 | FOLH1 (0.39) | MEN1KMT2AKCNH2ADRB1ACP1 | |
| SCHEMBL6267977 | 0.91 | PTPN2 (0.40) | MEN1KMT2AKCNH2L3MBTL1ALDH1A1 | |
| SCHEMBL6267975 | 0.91 | PTPN2 (0.40) | MEN1KMT2AKCNH2L3MBTL1ALDH1A1 | |
| SCHEMBL6272918 | 0.91 | KMT2A (0.39) | MEN1KMT2AKCNH2L3MBTL1ALDH1A1 | |
| SCHEMBL6272922 | 0.91 | KMT2A (0.39) | MEN1KMT2AKCNH2L3MBTL1ALDH1A1 | |
| SCHEMBL6273370 | 0.89 | LRRK2 (0.39) | KMT2AKCNH2ADRB1ADRB3CNR1 | |
| SCHEMBL6272451 | 0.89 | KCNH2 (0.40) | KCNH2ADRB1ADRB3 | |
| SCHEMBL6273369 | 0.89 | LRRK2 (0.39) | KMT2AKCNH2ADRB1ADRB3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |