⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11756439 | 0.86 | ALDH1A1 (0.38) | — | |
| SCHEMBL9714722 | 0.84 | MEN1 (0.33) | — | |
| SCHEMBL5047358 | 0.80 | CA12 (0.35) | — | |
| SCHEMBL5749958 | 0.78 | ALDH1A1 (0.35) | — | |
| SCHEMBL3739677 | 0.76 | TSHR (0.32) | — | |
| SCHEMBL728772 | 0.74 | TSHR (0.41) | — | |
| SCHEMBL2188530 | 0.73 | — | — | |
| SCHEMBL5949135 | 0.72 | TSHR (0.38) | — | |
| SCHEMBL11798925 | 0.71 | ALDH1A1 (0.38) | — | |
| SCHEMBL5948492 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050282863-A1 | Novel-N substituted dihydrobenzothiepino, dihydrobenzoxepino and tetrahydro benzocyclohepta indoles as selective estrogen receptor modulators | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-12-22 | — | — | US | claimed |
| WO-2005094833-A1 | NOVEL N-SUBSTITUTED DIHYDROBENZOTHIEPINO, DIHYDROBENZOXEPINO AND TETRAHYDRO BENZOCYCLOHEPTA INDOLES AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-10-13 | — | — | WO | claimed |
| US-9717801-B2 | Glycogen-based cationic polymers | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2017-08-01 | — | — | US | disclosed |
| US-20140378532-A1 | GLYCOGEN-BASED CATIONIC POLYMERS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2014-12-25 | — | — | US | disclosed |
| US-20050282863-A1 | Novel-N substituted dihydrobenzothiepino, dihydrobenzoxepino and tetrahydro benzocyclohepta indoles as selective estrogen receptor modulators | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-12-22 | — | — | US | disclosed |
| WO-2005094833-A1 | NOVEL N-SUBSTITUTED DIHYDROBENZOTHIEPINO, DIHYDROBENZOXEPINO AND TETRAHYDRO BENZOCYCLOHEPTA INDOLES AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-10-13 | — | — | WO | disclosed |
| US-20040180947-A1 | hypoglycemic activity or phoshodiesterase-V inhibitory activity; prophylaxis and treatment of impaired glucose tolerance disorder, diabetes (e.g., type II diabetes), diabetic complications | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |