Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 5/20 | 0.48 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRM8 | O00222 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.32 |
| ▸ | OAT | P04181 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Icofungipen SCHEMBL7791325 | 1.00 | GABRR1 (0.48) | GABRR1ABATGRM4CYP2C19TDP1 | |
| Icofungipen SCHEMBL3950387 | 1.00 | GABRR1 (0.48) | GABRR1ABATGRM4CYP2C19TDP1 | |
| Icofungipen SCHEMBL3950389 | 1.00 | GABRR1 (0.48) | GABRR1ABATGRM4CYP2C19TDP1 | |
| Icofungipen SCHEMBL6268839 | 1.00 | GABRR1 (0.48) | GABRR1ABATGRM4CYP2C19TDP1 | |
| Icofungipen SCHEMBL117349 | 1.00 | GABRR1 (0.48) | GABRR1ABATGRM4CYP2C19TDP1 | |
| SCHEMBL1030623 | 0.83 | GABRR1 (0.39) | GABRR1GRM4CYP2C19TDP1MEN1 | |
| SCHEMBL1030281 | 0.83 | GABRR1 (0.39) | GABRR1GRM4CYP2C19TDP1MEN1 | |
| SCHEMBL8413192 | 0.83 | GABRR1 (0.39) | GABRR1GRM4CYP2C19TDP1MEN1 | |
| SCHEMBL1030622 | 0.83 | GABRR1 (0.39) | GABRR1GRM4CYP2C19TDP1MEN1 | |
| SCHEMBL8261790 | 0.77 | GABRR1 (0.37) | GABRR1GRM4CYP2C19TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100302-A1 | SOLID STATE FORMS OF (-)-(1R,2S)-2-AMINO-4-METHYLENE-CYCLOPENTANECARBOXYLIC ACID | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (US) | 2005-10-27 | — | — | WO | disclosed |