Icofungipen

Icofungipen

SCHEMBL117349

C=C1C[C@H](N)[C@H](C(=O)O)C1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 5/20 0.48
ABAT P80404 1/20 0.34
GRM4 Q14833 4/20 0.32
CYP2C19 P33261 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
GRM8 O00222 1/20 0.32
GRM6 O15303 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
GABRR2 P28476 1/20 0.32
OAT P04181 1/20 0.32
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Icofungipen SCHEMBL7791325 1.00 GABRR1 (0.48) GABRR1ABATGRM4CYP2C19TDP1
Icofungipen SCHEMBL3950387 1.00 GABRR1 (0.48) GABRR1ABATGRM4CYP2C19TDP1
Icofungipen SCHEMBL3950389 1.00 GABRR1 (0.48) GABRR1ABATGRM4CYP2C19TDP1
Icofungipen SCHEMBL6268839 1.00 GABRR1 (0.48) GABRR1ABATGRM4CYP2C19TDP1
Icofungipen SCHEMBL6268842 1.00 GABRR1 (0.48) GABRR1ABATGRM4CYP2C19TDP1
SCHEMBL1030623 0.83 GABRR1 (0.39) GABRR1GRM4CYP2C19TDP1MEN1
SCHEMBL1030281 0.83 GABRR1 (0.39) GABRR1GRM4CYP2C19TDP1MEN1
SCHEMBL8413192 0.83 GABRR1 (0.39) GABRR1GRM4CYP2C19TDP1MEN1
SCHEMBL1030622 0.83 GABRR1 (0.39) GABRR1GRM4CYP2C19TDP1MEN1
SCHEMBL8261790 0.77 GABRR1 (0.37) GABRR1GRM4CYP2C19TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118548269-A AHMA type hydraulic operating mechanism travel test method 中国长江电力股份有限公司 2024-08-27 CN claimed
CN-118528007-A Maintenance method for AHMA type energy storage piston of operating mechanism 中国长江电力股份有限公司 2024-08-23 CN claimed
CN-118514037-A AHMA type disassembly and overhaul method for hydraulic operating mechanism 中国长江电力股份有限公司 2024-08-20 CN claimed
CN-118007273-A Method for preparing high ultraviolet light absorption capacity composite fiber membrane based on electrostatic spinning 浙江理工大学 2024-05-10 CN claimed
CN-116012687-A Image interaction fusion method for identifying tread defects of wheel set 湖南工业大学 2023-04-25 CN claimed
US-11311625-B2 Peptide-based multiple-drug delivery vehicle ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) 2022-04-26 US claimed
US-12606830-B2 Protected antibody-drug and aptamer-drug conjugates KOSAK KENNETH MICHAEL (US) 2026-04-21 US disclosed
EP-4306515-B1 3-HYDROXYADIPIC ACID 3,6-LACTONE COMPOSITION TORAY INDUSTRIES (JP) 2026-02-04 EP disclosed
US-12467016-B1 Air purification candle Glow Guardian, Inc. (US) 2025-11-11 US disclosed
US-12433949-B2 Sustained release delivery systems comprising traceless linkers NOVARTIS AG (CH) 2025-10-07 US disclosed
US-20250302953-A1 METHODS OF TREATING PATIENTS EXHIBITING A PRIOR FAILED THERAPY WITH HYPOIMMUNOGENIC CELLS SANA BIOTECHNOLOGY, INC. 2025-10-02 US disclosed
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 EP disclosed
CN-119886035-A Large-scale design-oriented high-efficiency area and line length optimization macro layout method 广东工业大学 2025-04-25 CN disclosed
EP-0805145-B1 Efficient and highly enantioselective process for the preparation of enantiomerically pure cylopentane-beta-amino acids BAYER AG (DE) 2001-10-31 EP disclosed
EP-0754678-B1 Improvement of physiological tolerance of pharmaceutical active beta-amino acids BAYER AG (DE) 2001-01-03 EP disclosed
EP-1043332-A1 Dipeptides comprising cyclopentan-beta-amino acids Bayer Aktiengesellschaft (DE) 2000-10-11 EP disclosed
US-5935988-A MIXTURES OF 2-AMINO-4-METHYLENECYCLOPENTANECARBOXYLIC ACID WITH ISOLEUCINE, ALANINE OR PROLINE BAYER AKTIENGESELLSCHAFT (DE) 1999-08-10 US disclosed
US-5877343-A Efficient and highly enantioselective process for the preparation of enantiomerically pure cyclopentane-β-amino acids BAYER AKTIENGESELLSCHAFT (DE) 1999-03-02 US disclosed
EP-0805145-A1 Efficient and highly enantioselective process for the preparation of enantiomerically pure cylopentane-beta-amino acids BAYER AG (DE) 1997-11-05 EP disclosed
EP-0754678-A2 Improvement of physiological tolerance of pharmaceutical active beta-amino acids BAYER AG (DE) 1997-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606830-B2 Protected antibody-drug and aptamer-drug conjugates PABPC1, PABPC4, ABCG2 GABRR1 4066/4885ABAT 1028/4885GRM4 1436/4885
US-12433949-B2 Sustained release delivery systems comprising traceless linkers ABCB11, ABCB1, GHRHR GABRR1 2273/4885ABAT 1214/4885GRM4 3357/4885
US-11311625-B2 Peptide-based multiple-drug delivery vehicle VIP, NGLY1, IAPP GABRR1 1004/4885ABAT 2927/4885GRM4 2730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.