Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 3/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186537 | 0.74 | CTSA (0.46) | PDPK1CTSANNMTFYN | |
| SCHEMBL15006457 | 0.74 | BAZ2B (0.47) | BAZ2B | |
| SCHEMBL8065855 | 0.73 | FYN (0.43) | PDPK1CTSANNMTFYN | |
| SCHEMBL22792229 | 0.73 | CTSA (0.48) | BAZ2BPDPK1CTSANNMT | |
| SCHEMBL13765790 | 0.69 | BAZ2B (0.42) | BAZ2B | |
| SCHEMBL13771995 | 0.69 | BAZ2B (0.42) | BAZ2B | |
| SCHEMBL15850232 | 0.69 | PDPK1 (0.33) | PDPK1CTSA | |
| SCHEMBL13159701 | 0.69 | — | — | |
| SCHEMBL1794376 | 0.66 | — | — | |
| SCHEMBL13080477 | 0.66 | NNMT (0.46) | BAZ2BNNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105065-A2 | THIAZOLE-BASED NITRIC OXIDE DONORS FOR TREATING INFLAMMATORY BOWEL DISEASES | RENOPHARM LTD. (IL) | 2005-11-10 | — | — | WO | disclosed |