Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264073 | 0.91 | SCD (0.30) | SCDFYN | |
| SCHEMBL279486 | 0.81 | SRC (0.32) | SCDFYNSRCZAP70SYK | |
| SCHEMBL6270216 | 0.80 | SRC (0.46) | SCDFYNSRCZAP70SYK | |
| SCHEMBL263495 | 0.74 | TP53 (0.31) | MAPT | |
| SCHEMBL259808 | 0.71 | HTT (0.43) | SRCZAP70SYKMAPT | |
| SCHEMBL259567 | 0.68 | CYP1A2 (0.33) | MAPT | |
| SCHEMBL6273995 | 0.65 | FYN (0.35) | SCDFYN | |
| SCHEMBL279469 | 0.64 | HTT (0.30) | SRCZAP70SYKMAPT | |
| SCHEMBL259331 | 0.64 | CDC7 (0.45) | MAPT | |
| SCHEMBL260409 | 0.64 | MAPT (0.51) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105065-A2 | THIAZOLE-BASED NITRIC OXIDE DONORS FOR TREATING INFLAMMATORY BOWEL DISEASES | RENOPHARM LTD. (IL) | 2005-11-10 | — | — | WO | disclosed |