Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 2/20 | 0.46 |
| ▸ | FYN | P06241 | 2/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 6/20 | 0.31 |
| ▸ | LMNA | P02545 | 5/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | TKT | P29401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL261442 | 0.75 | SRC (0.47) | SRCZAP70SYKTP53MAPT | |
| SCHEMBL6273995 | 0.73 | FYN (0.35) | FYNSCD | |
| SCHEMBL260103 | 0.68 | MAPT (0.56) | SRCZAP70SYKMAPTLMNA | |
| SCHEMBL260421 | 0.67 | LMNA (0.54) | TP53MAPTLMNATHRB | |
| SCHEMBL3372003 | 0.65 | MAPT (0.55) | TP53MAPTLMNATHRB | |
| SCHEMBL263873 | 0.65 | SRC (0.46) | SRCZAP70SYKTP53MAPT | |
| SCHEMBL279469 | 0.64 | HTT (0.30) | SRCZAP70SYKTP53MAPT | |
| SCHEMBL263398 | 0.64 | ALDH1A1 (0.45) | SRCZAP70SYKTP53THRB | |
| SCHEMBL259573 | 0.64 | HTR2B (0.48) | SRCZAP70SYKTP53MAPT | |
| SCHEMBL29044473 | 0.63 | SRC (0.39) | SRCZAP70SYKTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105065-A2 | THIAZOLE-BASED NITRIC OXIDE DONORS FOR TREATING INFLAMMATORY BOWEL DISEASES | RENOPHARM LTD. (IL) | 2005-11-10 | — | — | WO | disclosed |