Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.51 |
| ▸ | FCER2 | P06734 | 5/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP7 | P09237 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271888 | 0.85 | PTPN1 (0.47) | PTPN1FCER2MMP9MMP3PTPN2 | |
| SCHEMBL6271881 | 0.85 | PTPN1 (0.47) | PTPN1FCER2MMP9MMP3PTPN2 | |
| SCHEMBL6273945 | 0.83 | F2 (0.58) | PTPN1FCER2MMP9PTPN2PIN1 | |
| SCHEMBL6268162 | 0.80 | PTPN1 (0.52) | PTPN1FCER2MMP9MMP3PTPN2 | |
| SCHEMBL8276816 | 0.77 | FCER2 (0.48) | PTPN1FCER2MMP9MMP3PTPN2 | |
| SCHEMBL6269192 | 0.77 | FCER2 (0.48) | PTPN1FCER2MMP9MMP3PTPN2 | |
| SCHEMBL6269195 | 0.77 | FCER2 (0.48) | PTPN1FCER2MMP9MMP3PTPN2 | |
| SCHEMBL6273418 | 0.76 | REN (0.47) | PTPN1 | |
| SCHEMBL6271928 | 0.75 | PTPN1 (0.43) | PTPN1FCER2MMP9MMP3PTPN2 | |
| SCHEMBL6271955 | 0.74 | PTPN1 (0.43) | PTPN1FCER2MMP9MMP3PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105843-A2 | HIV PROTEASE INHIBITORS | ARPIDA A/S (DK) | 2005-11-10 | — | — | WO | claimed |
| WO-2005105843-A2 | HIV PROTEASE INHIBITORS | ARPIDA A/S (DK) | 2005-11-10 | — | — | WO | disclosed |
| WO-2005105843-A2 | HIV PROTEASE INHIBITORS | ARPIDA A/S (DK) | 2005-11-10 | — | — | WO | disclosed |