Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3285085 | 0.86 | MAPT (0.42) | MAPTFBP1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL3286190 | 0.83 | MAPT (0.41) | MAPTMAPK1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL30888289 | 0.69 | GAA (0.45) | MAPTMAPK1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL29197525 | 0.69 | GAA (0.45) | MAPTMAPK1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL3279707 | 0.67 | MAPT (0.39) | MAPTMAPK1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL28086988 | 0.64 | MAPT (0.49) | MAPTMAPK1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL10827920 | 0.63 | KMT2A (0.45) | MAPTSMN1; SMN2POLBALDH1A1RAB9A | |
| SCHEMBL3280358 | 0.63 | TDP1 (0.43) | MAPTSMN1; SMN2POLBALDH1A1RAB9A | |
| SCHEMBL311208 | 0.63 | MAPT (0.46) | MAPTMAPK1FBP1SMN1; SMN2POLB | |
| SCHEMBL22076878 | 0.62 | FBP1 (0.55) | MAPTFBP1SMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606447-A1 | OXIDATION SYSTEM CONTAINING A MACROCYCLIC METAL COMPLEX, THE PRODUCTION THEREOF AND ITS USE | Lanxess B.V. (NL) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004083516-A1 | OXIDATION SYSTEM CONTAINING A MACROCYCLIC METAL COMPLEX, THE PRODUCTION THEREOF AND ITS USE | LANXESS B.V. (NL) | 2004-09-30 | — | — | WO | disclosed |