Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 11/20 | 0.43 |
| ▸ | INPP5A | Q14642 | 6/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | INPP5B | P32019 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27826952 | 0.89 | INPPL1 (0.44) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL19305102 | 0.87 | INPPL1 (0.43) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL27826911 | 0.78 | INPPL1 (0.47) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL1821429 | 0.78 | INPPL1 (0.47) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL3287701 | 0.75 | SRC (0.41) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL6260390 | 0.74 | SRC (0.51) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL28379246 | 0.74 | INPPL1 (0.43) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL3289172 | 0.74 | INPPL1 (0.40) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL28891115 | 0.73 | INPPL1 (0.48) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL9243111 | 0.72 | INPPL1 (0.41) | INPPL1INPP5AAKT1INPP5BSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063777-A1 | BENZYLPHOSPHATE AND SUBSTITUTED BENZYLPHOSPHATE PRODRUGS FOR THE TREATMENT OF PULMONARY INFLAMMATION | CORUS PHARMA (US) | 2005-07-14 | — | — | WO | disclosed |