SCHEMBL3289172

SCHEMBL3289172

Cc1ccc(-c2ccc(OP(=O)(O)O)c(C(C)(C)C)c2C(C)(C)C)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 9/20 0.40
INPP5A Q14642 4/20 0.40
AKT1 P31749 1/20 0.40
INPP5B P32019 2/20 0.35
SRC P12931 2/20 0.34
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
S1PR1 P21453 2/20 0.32
S1PR3 Q99500 2/20 0.32
PTPN5 P54829 1/20 0.32
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
PDE3A Q14432 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ARF6 P62330 1/20 0.31
GRIN2C Q14957 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3287701 0.87 SRC (0.41) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL3289174 0.78 INPPL1 (0.39) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL27826911 0.78 INPPL1 (0.47) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL5936078 0.77 INPPL1 (0.43) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL11111474 0.75 KDM4E (0.40) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL8596411 0.75 INPPL1 (0.46) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL1821429 0.74 INPPL1 (0.47) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL6260390 0.74 SRC (0.51) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL6270791 0.74 INPPL1 (0.43) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL343312 0.73 INPPL1 (0.47) INPPL1INPP5AAKT1INPP5BSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723449-B2 Catalysts for synthesizing a polypropylene with a wide molecular weight distribution and use of the same CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2010-05-25 US claimed
US-20090023881-A1 Catalyst for synthesizing a polypropylene with a wide molecular weight distribution and use of the same CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2009-01-22 US claimed
US-7723449-B2 Catalysts for synthesizing a polypropylene with a wide molecular weight distribution and use of the same CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2010-05-25 US disclosed
US-20090023881-A1 Catalyst for synthesizing a polypropylene with a wide molecular weight distribution and use of the same CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2009-01-22 US disclosed