Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5839257 | 0.90 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL5957108 | 0.89 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL5837732 | 0.88 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL6256990 | 0.88 | P2RX7 (0.45) | P2RX7IL1B | |
| SCHEMBL6271005 | 0.87 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL5838640 | 0.85 | P2RX7 (0.49) | P2RX7 | |
| SCHEMBL6277956 | 0.85 | P2RX7 (0.43) | P2RX7IL1B | |
| SCHEMBL5838961 | 0.85 | P2RX7 (0.53) | P2RX7IL1B | |
| SCHEMBL5837065 | 0.84 | P2RX7 (0.51) | P2RX7 | |
| SCHEMBL5837236 | 0.84 | P2RX7 (0.54) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581507-A1 | BENZAMIDE INHIBITORS OF THE P2X7 RECEPTOR | Pfizer Products Inc. (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004058731-A1 | BENZAMIDE INHIBITORS OF THE P2X7 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2004-07-15 | — | — | WO | disclosed |