Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 6/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.51 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.51 |
| ▸ | EP300 | Q09472 | 1/20 | 0.51 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.51 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.51 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.51 |
| ▸ | F13A1 | P00488 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10659962 | 1.00 | BID (0.51) | BIDMCL1BCL2L1BAK1PPARA | |
| SCHEMBL18586488 | 0.93 | FOLH1 (0.50) | BIDMCL1BCL2L1BAK1PPARA | |
| SCHEMBL9330418 | 0.92 | BID (0.58) | BIDMCL1BCL2L1BAK1PPARA | |
| SCHEMBL211983 | 0.92 | BID (0.58) | BIDMCL1BCL2L1BAK1PPARA | |
| SCHEMBL10885451 | 0.90 | BID (0.56) | BIDMCL1BCL2L1BAK1PPARA | |
| SCHEMBL18586489 | 0.86 | FOLH1 (0.53) | BIDMCL1BCL2L1BAK1PPARA | |
| SCHEMBL5114102 | 0.86 | FOLH1 (0.56) | BIDMCL1BCL2L1BAK1PPARA | |
| SCHEMBL11052053 | 0.85 | BID (0.53) | BIDMCL1BCL2L1BAK1PPARA | |
| SCHEMBL503904 | 0.85 | MAPT (0.59) | F13A1MAPTRXFP1FOLH1SLC16A3 | |
| SCHEMBL9861570 | 0.85 | MAPT (0.59) | F13A1MAPTRXFP1FOLH1SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005039489-A2 | COMPOSITIONS AND METHODS FOR THE INHIBITION OF BONE GROWTH AND RESORPTION | POLYMERIX CORPORATION (US) | 2005-05-06 | — | — | WO | disclosed |