Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 7/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.58 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.58 |
| ▸ | BAK1 | Q16611 | 6/20 | 0.58 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.58 |
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.58 |
| ▸ | EP300 | Q09472 | 2/20 | 0.58 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.58 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.58 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | F7 | P08709 | 2/20 | 0.50 |
| ▸ | F3 | P13726 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330418 | 1.00 | BID (0.58) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL10885451 | 0.98 | BID (0.56) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL5114102 | 0.94 | FOLH1 (0.56) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL11052053 | 0.93 | BID (0.53) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL3033684 | 0.92 | BID (0.72) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL5424052 | 0.92 | BID (0.72) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL5519496 | 0.92 | BID (0.72) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL3258790 | 0.92 | BID (0.72) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL23277 | 0.92 | BID (0.72) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL301487 | 0.92 | BID (0.72) | BIDMCL1BCL2L1BAK1KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088405-B2 | Therapeutic compositions and methods | Rutgers, The State University of New Jersery (US) | 2012-01-03 | — | — | US | disclosed |
| US-8017714-B2 | Polyanhydrides with therapeutically useful degradation products | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-09-13 | — | — | US | disclosed |
| US-20100074937-A1 | POLYANHYDRIDES WITH THERAPEUTICALLY USEFUL DEGRADATION PRODUCTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2010-03-25 | — | — | US | disclosed |
| EP-1261347-B1 | THERAPEUTIC COMPOSITIONS AND METHODS FOR TREATING PERIODONTITIS WITH ANTIINFLAMATORY COMPOUNDS | UNIV RUTGERS (US) | 2009-09-30 | — | — | EP | disclosed |
| EP-2095817-A1 | Therapeutic compositions and methods | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2009-09-02 | — | — | EP | disclosed |
| US-7534852-B2 | Polyanhydrides with therapeutically useful degradation products | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2009-05-19 | — | — | US | disclosed |
| EP-1032605-B1 | POLYANHYDRIDES WITH THERAPEUTICALLY USEFUL DEGRADATION PRODUCTS | UNIV RUTGERS (US) | 2007-11-14 | — | — | EP | disclosed |
| US-20070213500-A1 | Polyanhydrides with therapeutically useful degradation products | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2007-09-13 | — | — | US | disclosed |
| US-20070014832-A1 | Therapeutic compositions and methods | RUTGERS, THE STATE UNIVESITY OF NEW JERSEY | 2007-01-18 | — | — | US | disclosed |
| US-7122615-B1 | Polyanhydrides with therapeutically useful degradation products | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2006-10-17 | — | — | US | disclosed |
| EP-1246627-B1 | POLYANHYDRIDES WITH BIOLOGICALLY ACTIVE DEGRADATION PRODUCTS | UNIV RUTGERS (US) | 2005-12-28 | — | — | EP | disclosed |
| US-20050249697-A1 | Compositions and methods for the inhibition of bone growth and resorption | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2005-11-10 | — | — | US | disclosed |
| WO-2005039489-A2 | COMPOSITIONS AND METHODS FOR THE INHIBITION OF BONE GROWTH AND RESORPTION | POLYMERIX CORPORATION (US) | 2005-05-06 | — | — | WO | disclosed |
| EP-1464673-A2 | Polyanhydrides with biologically active degradation products | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2004-10-06 | — | — | EP | disclosed |
| US-20040038948-A1 | Therapeutic compositions and methods | UHRICH KATHRYN E (US) | 2004-02-26 | — | — | US | disclosed |
| US-6685928-B2 | ADMINISTERING AN EFFECTIVE AMOUNT OF AN ANTI-INFLAMMATORY AGENT TO OR NEAR THE TISSUE TO PROMOTE HEALING OF TISSUE; USEFUL IN DENTAL AND ORTHOPEDIC APPLICATIONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2004-02-03 | — | — | US | disclosed |
| US-20030035787-A1 | Polyanhydrides with biologically active degradation products | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2003-02-20 | — | — | US | disclosed |
| US-6468519-B1 | DEPOLYMERIZATION OF BIOCOMPATIBLE TREATMENT AGENT PROVIDING ALPHAHYDROXYACIDS SUCH AS CITRIC ACID OR MALIC ACID; CREAMS, MOISTURIZERS, CLEANSERS, LOTIONS, SHAMPOOS, LIPSTICKS; SMOOTHER, CLEARER SKIN WITH FEWER WRINKLES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2002-10-22 | — | — | US | disclosed |
| US-20020106345-A1 | Therapeutic compositions and methods | POLYMERIX CORPORATION | 2002-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050249697-A1 | Compositions and methods for the inhibition of bone growth and resorption | SOST, BMP2, BMP1 | BID 410/4885MCL1 479/4885BCL2L1 390/4885 |
| US-20020106345-A1 | Therapeutic compositions and methods | COL2A1, BMP2, BMP4 | BID 3492/4885MCL1 1278/4885BCL2L1 644/4885 |
| US-20070014832-A1 | Therapeutic compositions and methods | COL2A1, BMP2, BMP4 | BID 3492/4885MCL1 1278/4885BCL2L1 644/4885 |
| US-20040038948-A1 | Therapeutic compositions and methods | COL2A1, BMP2, BMP4 | BID 3492/4885MCL1 1278/4885BCL2L1 644/4885 |
| US-20100074937-A1 | POLYANHYDRIDES WITH THERAPEUTICALLY USEFUL DEGRADATION PRODUCTS | AADAT, PAH, APEH | BID 1198/4885MCL1 4410/4885BCL2L1 3588/4885 |
| US-20030035787-A1 | Polyanhydrides with biologically active degradation products | SI, HAAO, GUSB | BID 3896/4885MCL1 3110/4885BCL2L1 3740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.