Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA4 | P22748 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271772 | 1.00 | FFAR4 (0.35) | FFAR4CA12CA1CA2CA4 | |
| SCHEMBL6273164 | 0.94 | LTB4R (0.38) | CA12CA1CA2CA4BCHE | |
| SCHEMBL6273161 | 0.94 | LTB4R (0.38) | CA12CA1CA2CA4BCHE | |
| SCHEMBL6273312 | 0.92 | CA12 (0.36) | CA12CA1CA2CA4BCHE | |
| SCHEMBL6273315 | 0.92 | CA12 (0.36) | CA12CA1CA2CA4BCHE | |
| SCHEMBL6272490 | 0.91 | KCNH2 (0.37) | NR1H3KCNH2ADRB1ADRB3 | |
| SCHEMBL6272491 | 0.91 | KCNH2 (0.37) | NR1H3KCNH2ADRB1ADRB3 | |
| SCHEMBL6267536 | 0.86 | KCNH2 (0.36) | KCNH2KMT2AMMP13CRHBPCRHR2 | |
| SCHEMBL6267534 | 0.86 | KCNH2 (0.36) | KCNH2KMT2AMMP13CRHBPCRHR2 | |
| SCHEMBL6272453 | 0.85 | ADRB3 (0.39) | NR1H3KCNH2KMT2ACRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |