Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16594058 | 1.00 | TSHR (0.58) | TSHRNAAATDP1L3MBTL1HRH4 | |
| SCHEMBL16594830 | 1.00 | TSHR (0.58) | TSHRNAAATDP1L3MBTL1HRH4 | |
| SCHEMBL16594607 | 1.00 | TSHR (0.58) | TSHRNAAATDP1L3MBTL1HRH4 | |
| SCHEMBL16594477 | 1.00 | TSHR (0.58) | TSHRNAAATDP1L3MBTL1HRH4 | |
| SCHEMBL27676364 | 0.98 | TSHR (0.61) | TSHRNAAATDP1L3MBTL1HRH4 | |
| SCHEMBL13226430 | 0.98 | TSHR (0.61) | TSHRNAAATDP1L3MBTL1HRH4 | |
| SCHEMBL31424945 | 0.94 | TSHR (0.52) | TSHRNAAATDP1L3MBTL1HRH4 | |
| SCHEMBL29230056 | 0.93 | TSHR (0.68) | TSHRNAAATDP1L3MBTL1HRH4 | |
| SCHEMBL29157555 | 0.91 | ALDH1A1 (0.50) | TSHRNAAATDP1L3MBTL1HRH4 | |
| SCHEMBL14524315 | 0.89 | TSHR (0.56) | TSHRNAAATDP1L3MBTL1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2202267-B1 | Plasticizer for biodegradable aliphatic polyester resins, and biodegradable resin composition | DAIHACHI CHEM IND (JP) | 2011-12-07 | — | — | EP | claimed |
| US-11819476-B2 | Rapamycin analogs and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| US-20230193067-A1 | METAL OXIDE COMPOSITION, LIGHT-EMITTING DEVICE USING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-06-22 | — | — | US | disclosed |
| EP-3145505-A1 | N-ACYLETHANOLAMINE HYDROLYZING ACID AMIDASE (NAAA) INHIBITORS AND THEIR USE THEREOF | Northeastern University (US) | 2017-03-29 | — | — | EP | disclosed |
| WO-2015179190-A1 | N-ACYLETHANOLAMINE HYDROLYZING ACID AMIDASE (NAAA) INHIBITORS AND THEIR USE THEREOF | NORTHEASTERN UNIVERSITY (US) | 2015-11-26 | — | — | WO | disclosed |
| WO-2005117985-A2 | LIPOPOLYPLEX CONSTRUCT WITH AN INTEGRIN BINDING PEPTIDE FOR DELIVERY OF NUCLEIC ACIDS, PEPTIDES OR DRUGS | UCL BIOMEDICA PLC (GB) | 2005-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11819476-B2 | Rapamycin analogs and uses thereof | RICTOR, MTOR, RPTOR | TSHR 3531/4885NAAA 4312/4885TDP1 3446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.