SCHEMBL8718176

SCHEMBL8718176

FC(F)(F)c1ccc(C(F)(F)F)cc1.FC(F)(F)c1cccc(C(F)(F)F)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.63
ALDH1A1 P00352 2/20 0.63
MAPK1 P28482 1/20 0.61
CES2 O00748 1/20 0.54
MGLL Q99685 1/20 0.54
KIF11 P52732 2/20 0.52
TAAR1 Q96RJ0 1/20 0.50
IDO1 P14902 2/20 0.48
HTR3E A5X5Y0 1/20 0.48
HTR3B O95264 1/20 0.48
HTR3A P46098 1/20 0.48
HTR3D Q70Z44 1/20 0.48
HTR3C Q8WXA8 1/20 0.48
HTR2A P28223 1/20 0.47
HTR2C P28335 1/20 0.47
HTR2B P41595 1/20 0.47
GRIN2B Q13224 1/20 0.46
P2RX1 P51575 1/20 0.46
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL62723 0.94 TSHR (0.67) TSHRALDH1A1MAPK1CES2MGLL
SCHEMBL30553105 0.91 TSHR (0.64) TSHRALDH1A1MAPK1CES2MGLL
Fluoride SCHEMBL30661872 0.91 TSHR (0.64) TSHRALDH1A1MAPK1CES2MGLL
SCHEMBL30252943 0.91 TSHR (0.64) TSHRALDH1A1MAPK1CES2MGLL
Benzene SCHEMBL8568955 0.91 TSHR (0.67) TSHRALDH1A1MAPK1CES2MGLL
SCHEMBL5698952 0.91 TSHR (0.64) TSHRALDH1A1MAPK1CES2MGLL
SCHEMBL28126330 0.91 TSHR (0.64) TSHRALDH1A1MAPK1CES2MGLL
Ethylene SCHEMBL28158839 0.88 TSHR (0.61) TSHRALDH1A1MAPK1CES2MGLL
Nitrogen SCHEMBL26667006 0.88 TSHR (0.61) TSHRALDH1A1MAPK1CES2MGLL
SCHEMBL13623768 0.86 TSHR (0.58) TSHRALDH1A1MAPK1CES2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744678-A NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY NIPPON OIL CO., LTD. (JP) 1998-04-28 US disclosed
EP-0758563-A1 OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT NIPPON OIL COMPANY, LTD. (JP) 1997-02-19 EP disclosed