Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19331126 | 0.92 | SLC22A6 (0.50) | SLC22A6SMN1; SMN2PDE4AMAPTGABRR1 | |
| SCHEMBL13062507 | 0.92 | SLC22A6 (0.50) | SLC22A6SMN1; SMN2PDE4AMAPTGABRR1 | |
| SCHEMBL6629736 | 0.92 | SLC22A6 (0.50) | SLC22A6SMN1; SMN2PDE4AMAPTGABRR1 | |
| SCHEMBL705762 | 0.92 | SLC22A6 (0.50) | SLC22A6SMN1; SMN2PDE4AMAPTGABRR1 | |
| Methacrylic Acid SCHEMBL28667288 | 0.82 | TGFBR1 (0.37) | SLC22A6SMN1; SMN2PDE4AMAPTGABRR1 | |
| E968 SCHEMBL20873561 | 0.81 | FFAR3 (0.59) | SLC22A6PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL4721742 | 0.81 | SLC22A6 (0.62) | SLC22A6SMN1; SMN2GPR84MAPTGABRR1 | |
| SCHEMBL3902208 | 0.81 | SLC22A6 (0.62) | SLC22A6SMN1; SMN2GPR84MAPTGABRR1 | |
| SCHEMBL5437765 | 0.81 | SLC22A6 (0.62) | SLC22A6SMN1; SMN2GPR84MAPTGABRR1 | |
| SCHEMBL3064786 | 0.79 | SLC22A6 (0.48) | SLC22A6SMN1; SMN2GPR84MAPTGABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005113777-A1 | MEANS AND METHODS FOR PRODUCING STRESS-RESISTANT PLANTS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2005-12-01 | — | — | WO | disclosed |