SCHEMBL6272707 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	LRRK2	Q5S007	2/20	0.40

▸	KCNH2	Q12809	1/20	0.37

▸	KCNA3	P22001	1/20	0.36

▸	KMT2A	Q03164	3/20	0.35

▸	L3MBTL1	Q9Y468	2/20	0.35

▸	ALDH1A1	P00352	3/20	0.35

▸	MEN1	O00255	2/20	0.35

▸	CYP2C9	P11712	1/20	0.34

▸	NAMPT	P43490	1/20	0.34

▸	NLRP3	Q96P20	1/20	0.34

▸	TDP1	Q9NUW8	1/20	0.34

▸	AKR1C3	P42330	1/20	0.34

▸	CYP51A1	Q16850	1/20	0.33

▸	GAA	P10253	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6272709	1.00	LRRK2 (0.40)	LRRK2KCNH2KCNA3KMT2AL3MBTL1
SCHEMBL6269051	0.93	LRRK2 (0.39)	LRRK2KCNH2KMT2AL3MBTL1ALDH1A1
SCHEMBL6269043	0.93	LRRK2 (0.39)	LRRK2KCNH2KMT2AL3MBTL1ALDH1A1
SCHEMBL6269807	0.92	LRRK2 (0.42)	LRRK2KCNH2KCNA3KMT2AL3MBTL1
SCHEMBL6272461	0.92	PTPN2 (0.40)	LRRK2KCNH2KMT2AL3MBTL1ALDH1A1
SCHEMBL6269805	0.92	LRRK2 (0.42)	LRRK2KCNH2KCNA3KMT2AL3MBTL1
SCHEMBL6272463	0.92	PTPN2 (0.40)	LRRK2KCNH2KMT2AL3MBTL1ALDH1A1
SCHEMBL6273580	0.91	AKR1C3 (0.37)	LRRK2KCNH2KMT2ACYP2C9NAMPT
SCHEMBL6273576	0.91	AKR1C3 (0.37)	LRRK2KCNH2KMT2ACYP2C9NAMPT
SCHEMBL6271201	0.91	KMT2A (0.38)	LRRK2KCNH2KMT2AL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2005110981-A1	AMINOALCOHOL DERIVATIVES	ASTELLAS PHARMA INC. (JP)	2005-11-24	—	—	WO	disclosed