Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.35 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273580 | 1.00 | AKR1C3 (0.37) | AKR1C3LRRK2POLBKMT2AGLP1R | |
| SCHEMBL6269051 | 0.92 | LRRK2 (0.39) | AKR1C3LRRK2POLBKMT2ALMNA | |
| SCHEMBL6269043 | 0.92 | LRRK2 (0.39) | AKR1C3LRRK2POLBKMT2ALMNA | |
| SCHEMBL6269814 | 0.92 | LRRK2 (0.40) | AKR1C3LRRK2POLBLMNAPKM | |
| SCHEMBL6269808 | 0.92 | LRRK2 (0.40) | AKR1C3LRRK2POLBLMNAPKM | |
| SCHEMBL6272707 | 0.91 | LRRK2 (0.40) | AKR1C3LRRK2KMT2ACYP2C9NAMPT | |
| SCHEMBL6272709 | 0.91 | LRRK2 (0.40) | AKR1C3LRRK2KMT2ACYP2C9NAMPT | |
| SCHEMBL6267521 | 0.90 | AKR1C3 (0.40) | AKR1C3LRRK2POLBKMT2ASPHK2 | |
| SCHEMBL6267524 | 0.90 | AKR1C3 (0.40) | AKR1C3LRRK2POLBKMT2ASPHK2 | |
| SCHEMBL6272461 | 0.89 | PTPN2 (0.40) | LRRK2KMT2ALMNASMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |