Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3983061 | 0.62 | PGR (0.44) | MAPTKDM4EATML3MBTL1 | |
| SCHEMBL6910639 | 0.62 | DRD3 (0.41) | MAPTKDM4EATML3MBTL1GAA | |
| SCHEMBL11255961 | 0.61 | ESR1 (0.51) | ALDH1A1HTR2AHTR2C | |
| SCHEMBL19099122 | 0.60 | HTR2B (0.36) | MAPTKDM4EATML3MBTL1POLB | |
| SCHEMBL20571939 | 0.60 | HTR2B (0.46) | MAPTKDM4EATML3MBTL1ALDH1A1 | |
| SCHEMBL17785801 | 0.60 | HTR2B (0.46) | MAPTKDM4EATML3MBTL1ALDH1A1 | |
| SCHEMBL8663605 | 0.60 | KDM4E (0.44) | MAPTKDM4EATML3MBTL1GAA | |
| SCHEMBL22050032 | 0.60 | HTR2B (0.46) | MAPTKDM4EATML3MBTL1ALDH1A1 | |
| SCHEMBL31511252 | 0.60 | HTR2B (0.46) | MAPTKDM4EATML3MBTL1ALDH1A1 | |
| SCHEMBL31000351 | 0.60 | HTR2B (0.46) | MAPTKDM4EATML3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095366-A1 | 7-ARYL 1,5-DIHYDRO-4,1-BENZOXAZEPIN-2(3H)-ONE DERIVATIVES AND THEIR USE AS PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2005-10-13 | — | — | WO | disclosed |