Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HAT1 | O14929 | 2/20 | 0.34 |
| ▸ | EP300 | Q09472 | 2/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.34 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272458 | 0.92 | NLRP3 (0.40) | GAAKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL6272705 | 0.91 | LRRK2 (0.39) | GAAKMT2AMEN1RAB9ANLRP3 | |
| SCHEMBL6271193 | 0.91 | KMT2A (0.41) | GAAKMT2AMEN1LMNARAB9A | |
| SCHEMBL6269313 | 0.91 | KMT2A (0.44) | KMT2AMEN1LMNARAB9AMAPK1 | |
| SCHEMBL6269042 | 0.90 | AKR1C3 (0.39) | GAAKMT2ARAB9ANLRP3POLB | |
| SCHEMBL6273572 | 0.90 | AKR1C3 (0.39) | GAAKMT2ARAB9ANLRP3POLB | |
| SCHEMBL6276815 | 0.88 | GAA (0.36) | GAAKMT2AMEN1RAB9ANLRP3 | |
| SCHEMBL6272911 | 0.88 | KMT2A (0.42) | KMT2AMEN1LMNARAB9AMAPK1 | |
| SCHEMBL6273802 | 0.85 | SIRT2 (0.41) | KMT2AMEN1LMNARAB9AMAPK1 | |
| SCHEMBL6270665 | 0.85 | LRRK2 (0.39) | GAAKMT2AMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |