Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 16/20 | 0.74 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.60 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627335 | 1.00 | FYN (0.74) | FYNHASPINMKNK1PIM1KCNH2 | |
| SCHEMBL1946949 | 0.85 | FYN (1.00) | FYNHASPINMKNK1PIM1KCNH2 | |
| SCHEMBL1944213 | 0.84 | FYN (0.81) | FYNHASPINMKNK1PIM1KCNH2 | |
| SCHEMBL1946263 | 0.84 | FYN (1.00) | FYNHASPIN | |
| SCHEMBL30521677 | 0.84 | FYN (1.00) | FYNHASPIN | |
| SCHEMBL1946927 | 0.84 | FYN (0.80) | FYNHASPINMKNK1PIM1KCNH2 | |
| SCHEMBL1945406 | 0.81 | FYN (0.76) | FYNHASPINMKNK1 | |
| SCHEMBL1944688 | 0.81 | FYN (1.00) | FYNHASPINPIM1KCNH2 | |
| SCHEMBL1946141 | 0.81 | FYN (0.71) | FYNHASPINPIM1KCNH2 | |
| SCHEMBL627334 | 0.80 | FYN (0.50) | FYNHASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |