Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13363702 | 0.91 | SMN1; SMN2 (0.46) | SMN1; SMN2EPHX1GAAKDM4EMAPT | |
| SCHEMBL1690354 | 0.91 | SMN1; SMN2 (0.46) | SMN1; SMN2EPHX1GAAKDM4EMAPT | |
| SCHEMBL6908741 | 0.91 | LMNA (0.46) | LMNAPLGPLATSMN1; SMN2GABRP | |
| SCHEMBL2215054 | 0.91 | SMN1; SMN2 (0.46) | SMN1; SMN2EPHX1GAAKDM4EMAPT | |
| SCHEMBL1741318 | 0.88 | LMNA (0.54) | LMNAPLGPLATSMN1; SMN2GABRP | |
| SCHEMBL7817617 | 0.88 | LMNA (0.54) | LMNAPLGPLATSMN1; SMN2GABRP | |
| SCHEMBL15139817 | 0.88 | LMNA (0.54) | LMNAPLGPLATSMN1; SMN2GABRP | |
| SCHEMBL135662 | 0.88 | LMNA (0.48) | LMNAPLGPLATSMN1; SMN2GABRP | |
| SCHEMBL135660 | 0.88 | LMNA (0.48) | LMNAPLGPLATSMN1; SMN2GABRP | |
| SCHEMBL265529 | 0.88 | LMNA (0.48) | LMNAPLGPLATSMN1; SMN2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606244-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | Abbott Laboratories (US) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004037769-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | ABBOTT LABORATORIES (US) | 2004-05-06 | — | — | WO | disclosed |