Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.46 |
| ▸ | PLK4 | O00444 | 2/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | RET | P07949 | 2/20 | 0.46 |
| ▸ | FER | P16591 | 2/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | MARK3 | P27448 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.46 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.46 |
| ▸ | STK3 | Q13188 | 2/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.46 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.46 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16797093 | 0.82 | NPSR1 (0.46) | DYRK1AMAPK1FLT3MEN1MAPT | |
| SCHEMBL8593143 | 0.75 | NPSR1 (0.43) | GSK3BCDK1CDK5GYS1MEN1 | |
| SCHEMBL1279682 | 0.75 | IKBKB (0.46) | MKNK2MAPK1GYS1MEN1MAPT | |
| SCHEMBL28724776 | 0.72 | GRM5 (0.44) | MAPK1MEN1MAPTHTTKMT2A | |
| SCHEMBL14519434 | 0.72 | MAPK14 (0.64) | PRKD3MAP4K4GSK3BPRKD2CLK4 | |
| SCHEMBL30639562 | 0.70 | MAPT (0.46) | RPS6KA3PLK4DAPK3DYRK3ROCK2 | |
| SCHEMBL2698649 | 0.70 | MAPK1 (0.44) | RPS6KA3PLK4DAPK3DYRK3ROCK2 | |
| SCHEMBL8195709 | 0.69 | GSK3B (0.41) | RPS6KA3PLK4DAPK3DYRK3ROCK2 | |
| SCHEMBL6180483 | 0.68 | PTGS2 (0.53) | CSNK1DMAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL8764358 | 0.68 | PTGS2 (0.52) | MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037227-A2 | SELECTIVE COX-2 INHIBITORS | MICROBIA, INC. (US) | 2005-04-28 | — | — | WO | claimed |