SCHEMBL6273567

SCHEMBL6273567

NC(=O)c1cc(S(=O)(=O)c2ccc(CCNC[C@@H](O)c3cccc(Cl)c3)cc2)ccc1O

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 20/20 0.56
ADRB1 P08588 12/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6273561 1.00 ADRB3 (0.56) ADRB3ADRB1
Hydrochloric Acid SCHEMBL6271738 0.99 ADRB3 (0.55) ADRB3ADRB1
Hydrochloric Acid SCHEMBL6271741 0.99 ADRB3 (0.55) ADRB3ADRB1
Hydrochloric Acid SCHEMBL6267776 0.94 ADRB3 (0.49) ADRB3ADRB1
Hydrochloric Acid SCHEMBL6267779 0.94 ADRB3 (0.49) ADRB3ADRB1
SCHEMBL6272943 0.91 ADRB3 (0.56) ADRB3ADRB1
SCHEMBL6272939 0.91 ADRB3 (0.56) ADRB3ADRB1
SCHEMBL6275239 0.91 ADRB3 (0.49) ADRB3ADRB1
SCHEMBL6275238 0.91 ADRB3 (0.49) ADRB3ADRB1
Hydrochloric Acid SCHEMBL6273522 0.90 ADRB3 (0.55) ADRB3ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005110981-A1 AMINOALCOHOL DERIVATIVES ASTELLAS PHARMA INC. (JP) 2005-11-24 WO claimed