Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 14/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275238 | 1.00 | ADRB3 (0.49) | ADRB3ADRB1ADRB2CYP2D6ADRA2A | |
| Hydrochloric Acid SCHEMBL6271845 | 0.99 | ADRB3 (0.49) | ADRB3ADRB1ADRB2CYP2D6ADRA2A | |
| Hydrochloric Acid SCHEMBL6271837 | 0.99 | ADRB3 (0.49) | ADRB3ADRB1ADRB2CYP2D6ADRA2A | |
| SCHEMBL6273561 | 0.91 | ADRB3 (0.56) | ADRB3ADRB1 | |
| SCHEMBL6273567 | 0.91 | ADRB3 (0.56) | ADRB3ADRB1 | |
| SCHEMBL6269362 | 0.91 | ADRB3 (0.49) | ADRB3ADRB1ADRB2CYP2D6ADRA2A | |
| SCHEMBL6269358 | 0.91 | ADRB3 (0.49) | ADRB3ADRB1ADRB2CYP2D6ADRA2A | |
| Hydrochloric Acid SCHEMBL6274474 | 0.90 | ADRB3 (0.52) | ADRB3ADRB1ADRB2CYP2D6ADRA2A | |
| Hydrochloric Acid SCHEMBL6274476 | 0.90 | ADRB3 (0.52) | ADRB3ADRB1ADRB2CYP2D6ADRA2A | |
| Hydrochloric Acid SCHEMBL6273788 | 0.90 | ADRB3 (0.49) | ADRB3ADRB1ADRB2CYP2D6ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | claimed |