Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 16/20 | 0.75 |
| ▸ | SLC27A2 | O14975 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | XBP1 | P17861 | 1/20 | 0.64 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347617 | 0.86 | ADAMTS5 (1.00) | ADAMTS5SLC27A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4201238 | 0.81 | ADAMTS5 (1.00) | ADAMTS5SLC27A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL24571119 | 0.81 | ADAMTS5 (0.74) | ADAMTS5SLC27A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL24571274 | 0.81 | ADAMTS5 (0.74) | ADAMTS5SLC27A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4354096 | 0.81 | ADAMTS5 (1.00) | ADAMTS5SLC27A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL22571289 | 0.80 | ADAMTS5 (0.69) | ADAMTS5SLC27A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL22571281 | 0.79 | ADAMTS5 (0.70) | ADAMTS5SLC27A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4982831 | 0.78 | ADAMTS5 (0.70) | ADAMTS5SLC27A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4356626 | 0.78 | ADAMTS5 (1.00) | ADAMTS5SLC27A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4985793 | 0.78 | ADAMTS5 (0.77) | ADAMTS5SLC27A2SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | claimed |