SCHEMBL6274205

SCHEMBL6274205

O=C(O)c1ccc(COC(=O)c2ccccc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.79
TDP1 Q9NUW8 3/20 0.79
SLC6A2 P23975 1/20 0.79
SLC6A3 Q01959 1/20 0.79
LMNA P02545 3/20 0.71
MEN1 O00255 1/20 0.67
ALDH1A1 P00352 4/20 0.61
MAPT P10636 3/20 0.61
HPGD P15428 2/20 0.61
RAB9A P51151 3/20 0.58
NPC1 O15118 2/20 0.58
NR4A1 P22736 1/20 0.56
NR4A2 P43354 1/20 0.56
NR4A3 Q92570 1/20 0.56
GAA P10253 1/20 0.55
RXRA P19793 3/20 0.53
RXRB P28702 2/20 0.53
RXRG P48443 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
CYP1A2 P05177 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL419555 0.94 KMT2A (0.81) KMT2ATDP1SLC6A2SLC6A3LMNA
Benzyl Benzoate SCHEMBL8359694 0.94 KMT2A (0.89) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL11703832 0.94 KMT2A (0.74) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL11777793 0.94 KMT2A (0.74) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL10916778 0.93 KMT2A (0.79) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL5085718 0.92 KMT2A (0.92) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL3078579 0.91 KMT2A (0.71) KMT2ATDP1SLC6A2SLC6A3LMNA
Paraben SCHEMBL30633385 0.89 LMNA (0.90) KMT2ATDP1SLC6A2SLC6A3LMNA
Paraben SCHEMBL28265402 0.89 LMNA (0.90) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL28580976 0.89 KMT2A (0.79) KMT2ATDP1SLC6A2SLC6A3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2005028674-A DOUBLE-SIDED RECORDING MEDIUM MITSUBISHI PAPER MILLS LTD 2005-02-03 JP disclosed
EP-0302516-A2 Optical article made of amorphous thermoplastic polyester resin MITSUBISHI RAYON CO., LTD. (JP) 1989-02-08 EP disclosed