Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | CCR1 | P32246 | 3/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSV | O60911 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045150 | 0.94 | CTSK (0.44) | CTSKCCR1P2RY12CTSSCTSV | |
| SCHEMBL4039142 | 0.93 | CTSK (0.45) | CTSKCCR1P2RY12CTSSCTSV | |
| SCHEMBL4038812 | 0.92 | CTSK (0.54) | CTSKCCR1P2RY12CTSSCTSV | |
| SCHEMBL4039713 | 0.92 | CTSK (0.45) | CTSKCCR1P2RY12CTSSCTSV | |
| SCHEMBL4044103 | 0.92 | CTSK (0.42) | CTSKCCR1P2RY12CTSSCTSV | |
| SCHEMBL4040752 | 0.92 | CTSK (0.54) | CTSKCCR1P2RY12CTSSCTSV | |
| SCHEMBL4042617 | 0.92 | CTSK (0.46) | CTSKCCR1P2RY12CTSSCTSV | |
| SCHEMBL4040062 | 0.91 | CTSK (0.40) | CTSKCCR1P2RY12CTSSCTSV | |
| SCHEMBL4043368 | 0.91 | CTSK (0.42) | CTSKCCR1P2RY12CTSSCTSV | |
| SCHEMBL4040448 | 0.90 | CTSK (0.49) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |