Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625768 | 0.95 | MAPT (0.57) | CA1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL8692897 | 0.92 | CA1 (0.66) | CA1CA2HDAC3HDAC1HDAC2 | |
| SCHEMBL4758298 | 0.92 | CA1 (0.57) | CA1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL18897627 | 0.92 | CA1 (0.70) | CA1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL24413361 | 0.90 | CA1 (0.65) | CA1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL4837793 | 0.89 | CA1 (0.63) | CA1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL14679151 | 0.87 | CA1 (0.60) | CA1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL12472110 | 0.87 | CA1 (0.48) | CA1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL15284035 | 0.87 | SMN1; SMN2 (0.58) | CA1CA2HDAC1HDAC8HDAC6 | |
| SCHEMBL5668241 | 0.86 | CA1 (0.50) | CA1CA2NAMPTIDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005035551-A2 | INHIBITORS OF PROTEINS THAT BIND PHOSPHORYLATED MOLECULES | INCYTE CORPORATION (US) | 2005-04-21 | — | — | WO | disclosed |