Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626483 | 0.85 | GCK (0.65) | GCKALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL185238 | 0.79 | GCK (0.77) | GCK | |
| SCHEMBL626912 | 0.77 | GCK (0.52) | GCKALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL627287 | 0.76 | GCK (0.51) | GCKALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL624715 | 0.73 | GCK (0.57) | GCK | |
| SCHEMBL6700167 | 0.70 | TSHR (0.62) | ALDH1A1LMNASMN1; SMN2MAPK1HSD17B10 | |
| SCHEMBL626672 | 0.69 | GCK (0.62) | GCKALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL9891915 | 0.68 | TSHR (0.66) | ALDH1A1LMNASMN1; SMN2MAPK1HSD17B10 | |
| SCHEMBL6164890 | 0.67 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL2651985 | 0.67 | GCK (0.60) | GCKALDH1A1LMNASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | claimed |
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | disclosed |