Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL324971 | 0.83 | TSHR (0.58) | TSHRHPGDNAAAHCAR2FAAH | |
| SCHEMBL11562743 | 0.82 | TSHR (0.47) | TSHRHPGDNAAAHCAR2CES2 | |
| SCHEMBL6126193 | 0.81 | TSHR (0.61) | TSHRHPGDNAAAHCAR2FAAH | |
| SCHEMBL8153023 | 0.81 | TSHR (0.61) | TSHRHPGDNAAAHCAR2FAAH | |
| SCHEMBL27511449 | 0.81 | TSHR (0.43) | TSHRHPGDNAAAHCAR2PLA2G2C | |
| SCHEMBL27413677 | 0.79 | TSHR (0.49) | TSHRCES2 | |
| SCHEMBL8197129 | 0.77 | TSHR (0.53) | TSHRHPGDNAAAHCAR2EPHX1 | |
| SCHEMBL14335765 | 0.77 | TSHR (0.40) | TSHRHPGDNAAAHCAR2CES2 | |
| SCHEMBL28055228 | 0.77 | TSHR (0.63) | TSHRHPGDNAAAHCAR2CES2 | |
| SCHEMBL10615595 | 0.76 | TSHR (0.50) | TSHRNAAAHCAR2CES2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390427-B1 | POLYMERIC EXCAVATION STRUCTURAL SUPPORT MEMBRANE | CONSTR RES & TECH GMBH (DE) | 2005-06-08 | — | — | EP | claimed |
| EP-1390427-A2 | POLYMERIC EXCAVATION STRUCTURAL SUPPORT MEMBRANE | Construction Research & Technology GmbH (DE) | 2004-02-25 | — | — | EP | claimed |
| US-20030119955-A1 | Polymeric structural support membrane | MBT HOLDING AG | 2003-06-26 | — | — | US | claimed |
| US-20020151637-A1 | Polymeric structural support membrane | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2002-10-17 | — | — | US | claimed |
| WO-2002070591-A2 | POLYMERIC EXCAVATION STRUCTURAL SUPPORT MEMBRANE | MBT HOLDING AG (CH) | 2002-09-12 | — | — | WO | claimed |
| EP-1390427-B1 | POLYMERIC EXCAVATION STRUCTURAL SUPPORT MEMBRANE | CONSTR RES & TECH GMBH (DE) | 2005-06-08 | — | — | EP | disclosed |
| EP-1390427-A2 | POLYMERIC EXCAVATION STRUCTURAL SUPPORT MEMBRANE | Construction Research & Technology GmbH (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-20030119955-A1 | Polymeric structural support membrane | MBT HOLDING AG | 2003-06-26 | — | — | US | disclosed |
| US-20020151637-A1 | Polymeric structural support membrane | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2002-10-17 | — | — | US | disclosed |
| WO-2002070591-A2 | POLYMERIC EXCAVATION STRUCTURAL SUPPORT MEMBRANE | MBT HOLDING AG (CH) | 2002-09-12 | — | — | WO | disclosed |