SCHEMBL8197129

SCHEMBL8197129

C=CCC(=C)C(=O)OCCCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.53
HPGD P15428 1/20 0.53
ATM Q13315 1/20 0.47
ALDH1A1 P00352 2/20 0.45
HCAR2 Q8TDS4 3/20 0.42
NAAA Q02083 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NPSR1 Q6W5P4 2/20 0.37
MAPT P10636 1/20 0.37
RAB9A P51151 1/20 0.37
RAD52 P43351 1/20 0.36
HTT P42858 1/20 0.36
CYP3A4 P08684 1/20 0.35
EPHX1 P07099 1/20 0.35
THRB P10828 1/20 0.35
LMNA P02545 1/20 0.35
ESR1 P03372 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL324971 0.95 TSHR (0.58) TSHRHPGDATMALDH1A1HCAR2
SCHEMBL8153023 0.93 TSHR (0.61) TSHRHPGDATMALDH1A1HCAR2
SCHEMBL6126193 0.93 TSHR (0.61) TSHRHPGDATMALDH1A1HCAR2
SCHEMBL10764632 0.89 TSHR (0.40) TSHRHPGDATMALDH1A1HCAR2
SCHEMBL28228107 0.86 TSHR (0.57) TSHRHPGDATMALDH1A1HCAR2
SCHEMBL15476392 0.84 TSHR (0.38) TSHRHPGDALDH1A1HTTCYP3A4
SCHEMBL250095 0.83 TSHR (0.47) TSHRHPGDATMALDH1A1HCAR2
SCHEMBL10762790 0.82 TSHR (0.50) TSHRHPGDATMALDH1A1HCAR2
SCHEMBL375032 0.80 TSHR (0.57) TSHRHPGDATMALDH1A1HCAR2
SCHEMBL2358456 0.80 ALDH1A1 (0.45) TSHRALDH1A1HCAR2NPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114031706-B Blue color weakness correcting lens and preparation method thereof 江苏视科新材料股份有限公司 2023-04-07 CN claimed
CN-114047642-A Red achromatopsia correcting lens and preparation method thereof 江苏视科新材料股份有限公司 2022-02-15 CN claimed
CN-114031706-A Blue color weakness correcting lens and preparation method thereof 江苏视科新材料股份有限公司 2022-02-11 CN claimed
CN-107759987-A A kind of 3D printing toughness reinforcing PLA material 黑龙江鑫达企业集团有限公司 2018-03-06 CN claimed
US-4690881-A Liquid developer for electrophotography RICOH CO., LTD. (JP) 1987-09-01 US claimed
CN-116059696-B Oil-water separation membrane for biodiesel wastewater and preparation method thereof 上海中器环保科技有限公司 2026-01-02 CN disclosed
CN-116685300-A Composition comprising one or more (bio) -alkanediols with an antioxidant 西姆莱斯股份公司 2023-09-01 CN disclosed
CN-115594817-B Acrylic acid modified polyurethane resin for pure water-based ink and preparation method thereof 广州立诺新材料科技有限公司 2023-05-09 CN disclosed
CN-116059696-A Oil-water separation membrane for biodiesel wastewater and preparation method thereof 上海中器环保科技有限公司 2023-05-05 CN disclosed
CN-114031706-B Blue color weakness correcting lens and preparation method thereof 江苏视科新材料股份有限公司 2023-04-07 CN disclosed
CN-114047642-A Red achromatopsia correcting lens and preparation method thereof 江苏视科新材料股份有限公司 2022-02-15 CN disclosed
CN-114031706-A Blue color weakness correcting lens and preparation method thereof 江苏视科新材料股份有限公司 2022-02-11 CN disclosed
US-5738746-A EMBEDDING OPTICAL ELEMENTS IN A THERMOPLASTIC BINDER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-14 US disclosed
EP-0510572-B1 Aqueous polyurethane-vinyl polymer dispersions for coating applications AIR PROD & CHEM (US) 1997-06-11 EP disclosed
EP-0754002-A1 CLOTHING BEARING RETROREFLECTIVE APPLIQUES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-01-22 EP disclosed
WO-1995026648-A2 CLOTHING BEARING RETROREFLECTIVE APPLIQUES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-10-12 WO disclosed
US-5173526-A Solvent resistance, wear resistance, flexibility AIR PRODUCTS AND CHEMICALS, INC. (US) 1992-12-22 US disclosed
EP-0510572-A2 Aqueous polyurethane-vinyl polymer dispersions for coating applications AIR PRODUCTS AND CHEMICALS, INC. (US) 1992-10-28 EP disclosed
WO-1990003411-A1 METHOD OF PREPARING REINFORCED RUBBER AND REINFORCED RUBBER PRODUCTS INSTITUTET POLYMERUTVECKLING AB (SE) 1990-04-05 WO disclosed
US-4690881-A Liquid developer for electrophotography RICOH CO., LTD. (JP) 1987-09-01 US disclosed