Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273756 | 0.94 | AAK1 (0.43) | AAK1SMN1; SMN2HSD17B10USP2ALDH1A1 | |
| SCHEMBL1651858 | 0.83 | AAK1 (0.41) | AAK1SMN1; SMN2HSD17B10USP2ALDH1A1 | |
| SCHEMBL6274839 | 0.79 | EPHX1 (0.47) | SMN1; SMN2HSD17B10USP2ALDH1A1HPGD | |
| SCHEMBL26583876 | 0.79 | EPHX1 (0.48) | SMN1; SMN2HSD17B10USP2ALDH1A1HPGD | |
| SCHEMBL17476756 | 0.79 | BTK (0.44) | AAK1ANPEPBTKSMN1; SMN2ALDH1A1 | |
| SCHEMBL6128504 | 0.79 | BTK (0.44) | AAK1ANPEPBTKSMN1; SMN2ALDH1A1 | |
| SCHEMBL14438406 | 0.79 | BTK (0.44) | AAK1ANPEPBTKSMN1; SMN2ALDH1A1 | |
| SCHEMBL254912 | 0.79 | BTK (0.44) | AAK1ANPEPBTKSMN1; SMN2ALDH1A1 | |
| SCHEMBL16169552 | 0.79 | BTK (0.44) | AAK1ANPEPBTKSMN1; SMN2ALDH1A1 | |
| SCHEMBL14210997 | 0.79 | BTK (0.44) | AAK1ANPEPBTKSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606244-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | Abbott Laboratories (US) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004037769-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | ABBOTT LABORATORIES (US) | 2004-05-06 | — | — | WO | disclosed |