Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.42 |
| ▸ | FAP | Q12884 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6274117 | 0.92 | EPHX1 (0.53) | EPHX1SMN1; SMN2HSD17B10DPP4PREP | |
| SCHEMBL26583876 | 0.88 | EPHX1 (0.48) | EPHX1SMN1; SMN2HSD17B10DPP4PREP | |
| SCHEMBL6271399 | 0.84 | PLG (0.39) | EPHX1SMN1; SMN2HSD17B10PSMB5PLG | |
| SCHEMBL6274792 | 0.79 | AAK1 (0.40) | EPHX1SMN1; SMN2HSD17B10ALDH1A1USP2 | |
| SCHEMBL1651905 | 0.78 | EPHX1 (0.55) | EPHX1SMN1; SMN2HSD17B10DPP4PREP | |
| SCHEMBL1449384 | 0.76 | EPHX1 (0.59) | EPHX1SMN1; SMN2HSD17B10DPP4PREP | |
| SCHEMBL15865900 | 0.76 | EPHX1 (0.59) | EPHX1SMN1; SMN2HSD17B10DPP4PREP | |
| SCHEMBL6271761 | 0.76 | KMT2A (0.41) | EPHX1SMN1; SMN2HSD17B10ALDH1A1NAAA | |
| SCHEMBL845001 | 0.74 | ALDH1A1 (0.52) | EPHX1SMN1; SMN2HSD17B10DPP4PREP | |
| SCHEMBL19745369 | 0.73 | EPHX1 (0.59) | EPHX1SMN1; SMN2HSD17B10DPP4PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606244-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | Abbott Laboratories (US) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004037769-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | ABBOTT LABORATORIES (US) | 2004-05-06 | — | — | WO | disclosed |